Puglia Villas - Vacation Rentals in Santo Spirito

Boutique Villa "Burchiello" with terrace on Green view From US $299
         

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10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Balcony/Terrace
Apartment Macine - Two Bedroom Villa, Sleeps 4 From US $362
         

Stalla - Villa with garden in the historic center From US $759
         

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9.6 (16 Reviews)
Villa
  • Air Conditioner
  • Parking
  • Pet Friendly
Pitti Flat - Belcanto Villas From US $269
         

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9.2 (41 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • Security/Safety

Luxury Places to Stay in Santo Spirito

Over 1209+ Luxury Places to Stay in or Near Santo Spirito
Lovely portion of property near Piazza Santo Spirito From US $9,719
         

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6.9 (25 Reviews)
Apartment
  • Air Conditioner
  • Security/Safety
  • Fireplace/Heating
GOLDEN LUXE - 4 suites, frescoes and garden From US $1,560
         

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9.3 (3 Reviews)
Apartment
  • Air Conditioner
  • View
  • Security/Safety
Historic Frescoes Apartment From US $1,406
         

New
Apartment
  • Air Conditioner
  • Parking
  • TV
Bocca's Apartment 8 From US $1,133
         

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8.8 (67 Reviews)
Apartment
  • Air Conditioner
  • Accessibility
  • Security/Safety
Centrale APT con terrazza a 5min dal Pitti! - HomeUnity From US $1,083
         

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7.9 (96 Reviews)
Apartment
  • Air Conditioner
  • Balcony/Terrace
  • Security/Safety
Lanfredini Firenze From US $1,000
         

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9.6 (37 Reviews)
Apartment
  • Air Conditioner
  • View
  • Ocean View
Private Apartments Leone From US $965
         

New
Apartment
  • Air Conditioner
  • Security/Safety
  • Fireplace/Heating
Cozy Basement Apartment From US $965
         

New
Apartment
  • Security/Safety
  • Child Friendly
  • Internet

Top-Rated Vacation Rentals with a Pool in Santo Spirito

Over 5+ Top-Rated Vacation Rentals with a Pool in or Near Santo Spirito
Hotel Torre di Bellosguardo From US $573
         

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8.4 (178 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Apartment set in a property with breathtaking view of Florence! From US $474
         

Torre di Bellosguardo From US $635
         

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9.0 (103 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Della Calza Spa & Foresteria From US $349
         

New
Hotel
  • Air Conditioner
  • Pool
  • Designated Smoking Area

Pet-Friendly Vacation Rentals in Santo Spirito

Over 193+ Pet-Friendly Vacation Rentals in or Near Santo Spirito
Casa Samelinda From US $135
         

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10.0 (5 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • View
Gina Guest House ⭐ San Frediano Florence Historical Center From US $277
         

9.2 (20 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
La Torre Del Cestello From US $166
         

9.0 (264 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Romantic Apartment With Garden 2 Minutes' Walk From Pitti Palace From US $152
         

9.8 (137 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Merville House Central Florence From US $153
         

9.8 (55 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly

Large Vacation Homes & Villas in Santo Spirito

Over 64+ Large Vacation Homes & Villas in or Near Santo Spirito
Affittacamere Il Chiostrino Guest House From US $187
         

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9.7 (277 Reviews)
House
  • Air Conditioner
  • Designated Smoking Area
  • Balcony/Terrace

Wheelchair Accessible Vacation Homes in Santo Spirito

Over 88+ Wheelchair Accessible Vacation Homes in or Near Santo Spirito
La Terrazza Sull'Arno From US $580
         

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9.4 (77 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • Designated Smoking Area
Boccaccio elegant apartment in Oltrarno From US $172
         

10.0 (13 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible
Ostello Tasso From US $85
         

8.6 (38 Reviews)
Hostel
  • Wheelchair Accessible
  • Accessibility
  • Security/Safety
Luxury awesome in San Frediano From US $431
         

10.0 (9 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible
Pontormo large apartment with fireplace in Oltrarno From US $358
         

10.0 (6 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible
Tiepolo romantic penthouse in the Oltrarno From US $171
         

10.0 (6 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible
Caravaggio frescoed big loft in Oltrarno From US $228
         

10.0 (4 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible
Tintoretto frescoed loft in the Oltrarno From US $186
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Wheelchair Accessible

Santo Spirito Vacation Rentals and Airbnb Places to Stay Under $200

Over 476+ Santo Spirito Vacation Rentals and Airbnb Places to Stay Under $200
Casa di Annusca From US $68
         

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9.4 (395 Reviews)
Bed & Breakfast
  • Air Conditioner
  • Child Friendly
  • Internet
SMART APT CLOSE TO PITTI PALACE IN THE OLD CENTER OF OLTRARNO From US $169
         

9.8 (146 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Security/Safety
Delightful flat in the heart of Florence From US $164
         

Cozy apartment in Oltrarno From US $163
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens
GuestHost - Industrial Chic Apartment in the heart of the historic center From US $129
         

7.8 (6 Reviews)
Apartment
  • Air Conditioner
  • Security/Safety
  • Wellness Facilities

Instantly Bookable Vacation Homes in Santo Spirito

Over 439+ Instantly Bookable Vacation Homes in or Near Santo Spirito
Apartment The basket of the Angels, Florence amazing views From US $477
         

10.0 (48 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Security/Safety
SMALL IRIS FLORENCE CENTER From US $229
         

9.4 (6 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Security/Safety
River Magic View apartment with parking From US $345
         

10.0 (67 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • TV
San Frediano Stile in Florence by Mmega From US $231
         

10.0 (13 Reviews)
Apartment
  • Air Conditioner
  • View
  • Ocean View
Ponte Vecchio, Art & Design in Historic Palace From US $548
         

10.0 (7 Reviews)
Apartment
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens
Raffaello apartment in Florence by Mmega From US $211
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • View
  • Ocean View

About Santo Spirito Vacation Rentals

With more than 11 Santo Spirito vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Puglia Villas and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at a rental property in Santo Spirito.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With Puglia Villas Santo Spirito, you have the flexibility of comparing different options of various deals with a single click. Looking for a rental by owner with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner, and other popular Airbnb-style properties in Santo Spirito. Places to stay near Santo Spirito are 1101.86 ft² on average, with prices averaging US $738 a night.

Puglia Villas makes it easy and safe to find and compare vacation rentals in Santo Spirito with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Top Rental Accommodation Types in Santo Spirito

Type Count
Villas 7
Holiday Apartments 3
Vacation Homes 1

Use these Quick Filters to Find a Vacation Rental in Santo Spirito

Pro Tip: Puglia Villas makes it easy to compare the best listings on Puglia Villas homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Puglia Villas homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Santo Spirito.

Weather in Santo Spirito

View the weather forecast for Santo Spirito before booking your Santo Spirito Vacation Rentals to confirm your best time to go.

December - February
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March - May
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June - August
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September - November
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Santo Spirito Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Santo Spirito?
How many vacation rentals are available in Santo Spirito?

Currently, the total number of properties listed in 2026 is over 11 in the Santo Spirito area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Santo Spirito.